Antibody DetailsProduct DetailsReactivity Species Mouse Host Species Armenian Hamster Immunogen G8 mouse T cells Product Concentration 0.2 mg/ml Formulation This DyLight® 488 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. Product Preparation The antibody was purified by protein a chromatography and conjugated to DyLight 488 under optimal conditions. Storage and Handling This DyLight® 488 conjugate is stable when stored at 2-8°C. Do not freeze. Country of Origin USA Shipping Next Day 2-8°C Excitation Laser Blue Laser (493 nm) RRIDAB_2894355 Applications and Recommended Usage? Quality Tested by Leinco For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. Each lot of this antibody is quality control tested. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Armenian Hamster Anti-Mouse Vγ 2 T-Cell Receptor (Vγ 2 TCR) (Clone UC3-10A6) recognizes an epitope on Mouse Vγ 2 TCR. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. This antibody reacts with Vγ 2 T-C Antigen Distribution Vγ 2 T-Cell Receptor (TCR)-bearing T lymphocytes make up a significant proportion of γδ TCR-bearing cells in the late fetal and adult thymus and adult peripheral lymphoid tissues and lung. Background The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules. Antigen DetailsProtein Function Might play a role in a previously unrecognized form of immunological surveillance for stress-induced self-antigens. PubMed Research Area Adaptive Immunity . Immunology References & CitationsHedrick, S. M. et al. (1990) Nature. 343:714
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Formats Available
Prod No. | Description |
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T554 |
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T212 |
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T219 |
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T353 |
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T211 |
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T213 |
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T594 |
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T704 |
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T210 |
