Antibody DetailsProduct DetailsReactivity Species Mouse Host Species Armenian Hamster Immunogen Purified Recombinant Mouse TCR (>98%) Product Concentration 0.5 mg/ml Formulation This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. Storage and Handling This purified antibody is stable when stored at 2-8°C. Do not freeze. Country of Origin USA Shipping Next Day Ambient RRIDAB_2892973 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity This antibody reacts with Vγ 2 T-Cell Receptor (TCR)-bearing T lymphocytes. Antigen Distribution Vγ 2 T-Cell Receptor (TCR)-bearing T lymphocytes make up a significant proportion of γδ TCR-bearing cells in the late fetal and adult thymus and adult peripheral lymphoid tissues and lung. Background The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules. Antigen DetailsProtein Function Might play a role in a previously unrecognized form of immunological surveillance for stress-induced self-antigens. PubMed Research Area Adaptive Immunity . Immunology References & CitationsHedrick, S. M. et al. (1990) Nature. 343:714 Technical Protocols |
Formats Available
Prod No. | Description |
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T554 |
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T212 |
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T219 |
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T353 |
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T211 |
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T213 |
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T594 |
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T704 |
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T210 |
