Anti-Calcineurin A (Catalytic) Antibody (56336)
Data
Detection of Calcineurin A in rat brain lysate (Lane 1) and mouse brain lysate (Lane 2). - -
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Antibody DetailsProduct DetailsReactive Species Bovine ⋅ Canine ⋅ Hamster ⋅ Human ⋅ Mouse ⋅ Rabbit ⋅ Rat Host Species Rabbit Immunogen Synthetic peptide corresponding to aa 264-283 of human Calcineurin A conjugated to KLH. This sequence is identical in rat and mouse calcineurin A. Product Concentration Lot Specific Formulation PBS, 50% glycerol, 0.09% sodium azide State of Matter Liquid Product Preparation Purified by protein A affinity chromatography Storage and Handling This antibody is stable for at least one (1) year at -20°C. Store in appropriate aliquots to avoid multiple freeze/thaw cycles. Regulatory Status Research Use Only Country of Origin USA Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco Immunoblotting: Use at 1-5ug/mL. A band of ~61kDa is detected.
These are recommended concentrations. Endusers should determine optimal concentrations for their application. Additional Applications Reported In Literature ? IP, WB Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity This antibody recognizes human, mouse, rat, rabbit, canine, bovine, porcine, chicken, monkey, hamster, and Drosophila Calcineurin A. Background Calcineurin is a Ca+2/calmodulin-dependent serine/threonine protein phosphatase. The active enzyme is a heterodimer consisting of a catalytic A subunit and a myristylated regulatory B subunit that binds calcium. It controls the translocation of nuclear factors from the cytosol into the nucleus of activated T cells. Calcineurin is a target of immunosuppressive drugs such as cyclosporin A and FK506. NCBI Gene Bank ID Research Area Neuroscience References & CitationsTechnical Protocols  Certificate of Analysis |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
