Anti-Cytochrome P450 Antibody (13006)
Data
Detection of cytochrome P450 in human liver microsomes (Lane 2), rat liver microsomes (Lane 3), mouse liver microsomes (Lane 4), rabbit liver microsomes (Lane 5). - -
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Antibody DetailsProduct DetailsReactivity Species Canine ⋅ Guinea Pig ⋅ Human ⋅ Monkey ⋅ Mouse ⋅ Rabbit ⋅ Rat Host Species Rabbit Immunogen Native rat cytochrome P450. Product Concentration Lot Specific Formulation PBS, pH 7.2, 50% glycerol, 0.09% sodium azide. State of Matter Liquid Product Preparation Purified by protein A affinity chromatography Storage and Handling This antibody is stable for at least one (1) year at -20°C. Country of Origin USA Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco Immunoblotting: Use at 1-5ug/mL. A band of ~50-55kDa is detected.
These are recommended concentrations. Endusers should determine optimal concentrations for their application. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Rabbit Polyclonal Antibody specific to Cytochrome P450 Background Cytochrome p450 is a highly conserved and diverse family of heme-containing proteins that function in the metabolism of numerous endogenous and exogenous substrates.The human genome encodes 57 p450 genes divided among 18 families which together account for the diversity of substrates metabolized. p450 is the primary conjugating enzyme in phase I metabolism and detoxification of endogenous and exogenous compounds and are primarily localized to the inner membranes of mitochondria and the ER. Eukaryotic microsomal cytochrome p450 enzymes receive electrons from the FAD- and FMN-containing enzyme NADPH:cytochrome p450 reductase. Antigen DetailsResearch Area Enzymes References & CitationsTechnical Protocols |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
