Anti-Mouse VEGF
Anti-Mouse VEGF
Product No.: V104
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Target VEGF Product Type Polyclonal Antibody Alternate Names Vascular Endothelial Growth Factor, VEGFA, MGC70609, VPF, VAS, Folliculostellate Cell-Derived Growth Factor, Glioma-Derived Endothelial Cell Mitogen Applications ELISA Cap , IHC FF , N , WB |
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Antibody DetailsProduct DetailsReactive Species Mouse Host Species Goat Immunogen Purified Recombinant Mouse VEGF (>98%) Endotoxin Level <0.04 EU/µg as determined by the LAL method Formulation This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.4 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present. State of Matter Lyophilized Storage and Handling The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months. Country of Origin USA Shipping Next Day Ambient RRIDAB_2832131 Applications and Recommended Usage? Quality Tested by Leinco Western Blot: Suitable for use at concentration of 0.1 µg/mL. ELISA Capture: Suitable for use at concentration of 0.2-0.8 µg/mL Additional Applications Reported In Literature ? Immunohistochemistry: Suitable for use at concentration of 5-15 µg/mL Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Rabbit Anti-Mouse Vascular Endothelial Growth Factor (VEGF) recognizes Mouse VEGF. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research. Background Vascular endothelial growth factor (VEGF), a potent proangiogenic cytokine1 is the key signal used by oxygen-hungry cells to promote growth of blood vessels. It binds to specialized receptors on the surfaces of endothelial cells and directs them to build new vessels.2 VEGF are crucial regulators of vascular development during embryogenesis (vasculogenesis) and blood-vessel formation in the adult (angiogenesis). Abnormal VEGF function is associated with inflammatory diseases including atherosclerosis, and hyperthyroidism.3,4,5,6 PubMed NCBI Gene Bank ID UniProt.org References & Citations1. Folkman, J. et al. (2008) FASEB J. 22:3728 2. Goodsell, DS. et al. (2002) The Oncologist 7:569 3. Mugishima, H. et al. (2006) J Atheroscler Thromb. 13:130 4. Claesson-Welsh, L. et al. (2006) Exp Cell Res. 312:549 5. Claesson-Welsh, L. et al. (1999) Trends Biochem Sci. 28:488 6. Ellis, LM. et al. (2005) J Clin Oncol. 23:1011 Technical Protocols IHC FF N  Certificate of Analysis |
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
