COVID-19 Virus and antibodies attacking

Leinco Technologies offers an extensive portfolio of antibodies to both SARS-CoV and SARS-CoV-2 structural proteins. These antibodies target the virus envelope, matrix, spike, spike intermediate domain, spike NTD, spike RBD, Nucleocapsid, and others. Leinco’s SARS-CoV-2 monoclonal antibodies are sequenced from human survivors of COVID-19. Evidence has shown that antibodies against SARS-CoV can cross-neutralize against SARS-CoV-21.

In addition, Leinco offers Anti-human IgG and Anti-human IgM antibodies in their In vivo GOLD™ functional grade specifications, providing a high purity level of > 95%, one of the highest in the industry. When infection occurs and samples are taken, M Immunoglobulins (IgM) provide the body’s first line of defense and detection reveals the recent exposure to the virus. Whereas, G Immunoglobulins (IgG) possess long-term immunity and immunological memory, and detection reveals exposure to virus occurred several weeks earlier2.

While SARS-CoV-2 immunological and cell response data is still lacking, Leinco’s antibodies are available for continuous support of disease prevention and treatment. Leinco also assures that all antibodies adhere to defined quality criteria within our ISO 9000:2015 and cGMP compliant manufacturing standards. A full list of Leinco’s available and in development polyclonal and monoclonal antibodies are below.

SARS-CoV-2 Recombinant Monoclonal Antibodies

Product
Clone
Applications
Prod No.
Package Size
1C7C7
ELISA
IHC
WB
LT7000
100 µg
500 µg
2146
ELISA
IHC
LT2005
50 µg
2146
ELISA
IHC
LT2010
50 µg
2146
ELISA
IHC
LT2000
1 mg
100 µg
500 µg
2215
ELISA
LT6000
1 mg
100 µg
500 µg
2165
ELISA
IHC
LT1905
50 µg
2165
ELISA
IHC
LT1910
50 µg
2196
ELISA
LT8005
50 µg
2196
ELISA
LT8010
50 µg
2165
ELISA
IHC
N
LT1900
1 mg
100 µg
500 µg
2196
ELISA
LT8000
1 mg
100 µg
500 µg
2355
ELISA
LT5000
1 mg
100 µg
500 µg
2381
ELISA
LT4000
1 mg
100 µg
500 µg
2838
ELISA
LT3000
1 mg
100 µg
500 µg

Anti-SARS-CoV-2 Spike Coming soon.

Second-Step Antibodies For Serology

Product
Clone
Applications
Prod No.
Package Size
HP6043
ELISA
FC
I-124
0.25 mg
HP6043
ELISA
FC
I-1193
0.25 mg
HB57
ELISA
FC
I-121
0.25 mg
HB57
ELISA
FC
I-1202
0.25 mg

Additional Conjugates Available for Anti-Human IgM µ-Chain Specific and Anti-Human IgG Fc Specific include: APC, Biotin, FITC, PE, HRP, PerCP, Dylight® 488, Dylight® 550, Dylight® 594, Dylight® 650, Dylight® 755.

SARS-CoV-2 Polyclonal Antibodies

Product
Applications
Prod No.
Package Size
ELISA
IF
IHC FFPE
WB
A314
0.1 mg
ELISA
IF
IHC FFPE
WB
A313
0.1 mg
ELISA
IF
IHC FFPE
WB
A315
0.1 mg
ELISA
IF
IHC FFPE
WB
A316
0.1 mg
ELISA
S538
0.1 mg
ELISA
S536
0.1 mg
ELISA
S539
0.1 mg
ELISA
S543
0.1 mg
ELISA
WB
S541
0.1 mg
ELISA
WB
S542
0.1 mg
ELISA
S544
0.1 mg
ELISA
S537
0.1 mg
ELISA
IF
WB
S540
0.1 mg
  1. di Mauro Gabriella, et al. 2020, International Immunopharmacology 84
  2. Hoffmann et al., 2020, Cell 181, 271–280