Recombinant Human MIP-1α (CCL3L1)

Chemokine (C-C motif) ligand 3-like 1, also known as CCL3L1 is a member of the CC chemokine family that exhibits a variety of pro-inflammatory activities including chemotaxis, and functional and proliferative activation of leukocytes, lymphocytes and macrophages.¹ CCL3L1 a potent human immunodeficiency virus-1 (HIV-1)-suppressive chemokine and ligand for the HIV co-receptor CCR5.² CCL3L1-CCR5 genotype may provide critical guidance for optimizing the design and evaluation of HIV-1 vaccine trials and prevention programs.³

P16619.1

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Ala24

Lyophilized

The predicted molecular weight of Recombinant Human CCL3L1 is Mr 7.8 kDa.

This recombinant protein was lyophilized from a 0.2 μm filtered solution in 35% acetonitrile (CH₃CN) and 0.1% trifluoroacetic acid (TFA).

This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

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1. Emi, M. et al. (2004) J Neurooncol. 70: 301
2. Ahuja, SK. et al. (2005) Science 307: 1434
3. Ahuja, SK. et al. (2008) PLoS One 3: e3671