COVID-19 Virus and antibodies attacking

Leinco Technologies offers an extensive portfolio of antibodies to both SARS-CoV and SARS-CoV-2 structural proteins. These antibodies target the virus envelope, matrix, spike, spike intermediate domain, spike NTD, spike RBD, Nucleocapsid, and others. Leinco’s SARS-CoV-2 monoclonal antibodies are sequenced from human survivors of COVID-19. Evidence has shown that antibodies against SARS-CoV can cross-neutralize against SARS-CoV-21.

In addition, Leinco offers Anti-human IgG and Anti-human IgM antibodies in their In vivo GOLD™ functional grade specifications, providing a high purity level of > 95%, one of the highest in the industry. When infection occurs and samples are taken, M Immunoglobulins (IgM) provide the body’s first line of defense and detection reveals the recent exposure to the virus. Whereas, G Immunoglobulins (IgG) possess long-term immunity and immunological memory, and detection reveals exposure to virus occurred several weeks earlier2.

While SARS-CoV-2 immunological and cell response data is still lacking, Leinco’s antibodies are available for continuous support of disease prevention and treatment. Leinco also assures that all antibodies adhere to defined quality criteria within our ISO 9000:2015 and cGMP compliant manufacturing standards. A full list of Leinco’s available and in development polyclonal and monoclonal antibodies are below.

SARS-CoV-2 Recombinant Monoclonal Antibodies

Nucleocapsid Mabs

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- -
Product
Pkg. Sizes
Clone:
Applications:
ELISA
IHC
WB
Prod No:LT7000
100 µg
500 µg
Clone:
Applications:
ELISA
Prod No:LT7081
50 µg
Clone:
Applications:
ELISA
Prod No:LT7082
50 µg
100 µg
500 µg
Clone:
Applications:
ELISA
Prod No:LT7031
50 µg
Clone:
Applications:
ELISA
Prod No:LT7032
50 µg
100 µg
500 µg
Clone:
Applications:
ELISA
Prod No:LT7061
50 µg
Clone:
Applications:
ELISA
Prod No:LT7062
50 µg
100 µg
500 µg
124

Spike (NTD and RBD) Mabs

- -
- -
Product
Pkg. Sizes
Clone:
Applications:
ELISA
IHC
Prod No:LT2005
50 µg
Clone:
Applications:
ELISA
IHC
Prod No:LT2010
50 µg
Clone:
Applications:
ELISA
IHC
Prod No:LT2000
100 µg
500 µg
100 µg
500 µg
100 µg
500 µg
Clone:
Applications:
ELISA
IHC
Prod No:LT1905
50 µg
Clone:
Applications:
ELISA
IHC
Prod No:LT1910
50 µg
Clone:
Applications:
ELISA
Prod No:LT8005
50 µg
Clone:
Applications:
ELISA
Prod No:LT8010
50 µg
100 µg
500 µg
12

Second-Step Antibodies For Serology

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- -
Product
Pkg. Sizes
Prod No:I-124
Clone:
HP6043
Applications:
ELISA
FC
0.25 mg
0.25 mg
Prod No:I-121
Clone:
HB57
Applications:
ELISA
FC
0.25 mg
Prod No:I-1202
Clone:
HB57
Applications:
ELISA
FC
in vivo
0.25 mg

Additional Conjugates Available for Anti-Human IgM µ-Chain Specific and Anti-Human IgG Fc Specific include: APC, Biotin, FITC, PE, HRP, PerCP, Dylight® 488, Dylight® 550, Dylight® 594, Dylight® 650, Dylight® 755.

SARS-CoV-2 Polyclonal Antibodies

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- -
Product
Pkg. Sizes
Prod No:A314
Applications:
ELISA
IF
IHC FFPE
WB
0.1 mg
20 µg
Prod No:A313
Applications:
ELISA
IF
IHC FFPE
WB
0.1 mg
20 µg
Prod No:A315
Applications:
ELISA
IF
IHC FFPE
WB
0.1 mg
20 µg
Prod No:A316
Applications:
ELISA
IF
IHC FFPE
WB
0.1 mg
20 µg
Prod No:S538
Applications:
ELISA
0.1 mg
20 µg
Prod No:S536
Applications:
ELISA
0.1 mg
20 µg
Prod No:S539
Applications:
ELISA
0.1 mg
20 µg
0.1 mg
20 µg
Prod No:S541
Applications:
ELISA
WB
0.1 mg
20 µg
Prod No:S542
Applications:
ELISA
WB
0.1 mg
20 µg
Prod No:S544
Applications:
ELISA
0.1 mg
20 µg
Prod No:S537
Applications:
ELISA
0.1 mg
20 µg
Prod No:S540
Applications:
ELISA
IF
WB
0.1 mg
20 µg
  1. di Mauro Gabriella, et al. 2020, International Immunopharmacology 84
  2. Hoffmann et al., 2020, Cell 181, 271–280