Anti-Mouse IFN-γ (Clone R4-6A2) – PerCP

Purified Mouse IFN-γ

This PerCP conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.

This PerCP conjugate is stable when stored at 2-8°C. Do not freeze.

Next Day 2-8°C

Rat Anti-Mouse Interferon Gamma (IFN-γ) (Clone R4-6A2) recognizes an epitope on Mouse IFN-γ. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.¹ It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.² IFN-γ has antiviral, immunoregulatory, and anti-tumour properties.³

1. Goeddel DV et al. (1982) Nature 298: 859 2. Wilson CB et al. (2007) Adv. Immunol. 96: 41 3. Hume DA et al. (2004) J Leukoc Biol. 75: 163