The “Cytokine Storm” and Inflammatory Response to SARS-CoV-2
SARS-CoV-2 infection in patients has shown increased secretion of IL-1β, IFN-γ, IP-10/CXCL10, MCP-1/CCL2, IL-4, and IL-10. In addition, the infection has shown elevated levels of inflammatory cytokines such as IL-2, IL-6, IL-7, IL-10, G-CSF, IP-10/CXCL10, MCP-1/CCL2, MIP-1A, and TNF-α generating possible “cytokine storm”1,2. The treatment of cytokine storm has become increasingly important in helping coronavirus patients. Studies have shown that the IL-6R (Interleukin-6 Receptor) plays an important role in alleviating Cytokine Release Syndrome (CRS)2. While causes for inflammatory responses remain widely unknown, Leinco can assist researchers in providing many of these cytokines.
SARS-CoV-2 Increased Secretion & Inflammation of Cytokines
Cytokines
Product | Clone | Applications | Prod No. | Package Size |
|---|---|---|---|---|
I-202 |
10 µg ⋅ 50 µg |
|||
G123 |
25 µg ⋅ 5 µg |
|||
G124 |
10 µg ⋅ 50 µg ⋅ 500 µg |
|||
I-179 |
100 µg |
|||
I-193 |
10 µg ⋅ 25 µg ⋅ 5 µg |
|||
I-214 |
25 µg ⋅ 5 µg |
|||
I-196 |
1.0 mg ⋅ 10 µg ⋅ 100 µg ⋅ 500 µg |
|||
I-198 |
1 mg ⋅ 100 µg ⋅ 25 µg ⋅ 500 µg |
|||
I-183 |
10 µg ⋅ 25 µg ⋅ 5 µg |
|||
I-184 |
10 µg ⋅ 50 µg |
Antibodies to Cytokines
Additional conjugates available for each.
Product | Clone | Applications | Prod No. | Package Size |
|---|---|---|---|---|
33036 |
CyTOF® ⋅ ELISA Cap ⋅ FC ⋅ N |
C1389 |
100 µg ⋅ 25 µg ⋅ 500 µg |
|
CyTOF® ⋅ ELISA Indirect ⋅ FC ⋅ ICC ⋅ IHC ⋅ N |
I-160 |
100 µg ⋅ 25 µg |
||
3316 |
ELISA Cap ⋅ N |
G664 |
100 µg ⋅ 25 µg ⋅ 500 µg |
|
N ⋅ WB |
G114 |
100 µg ⋅ 25 µg |
||
6804 |
CyTOF® ⋅ ELISA Cap ⋅ FC |
G675 |
100 µg ⋅ 25 µg ⋅ 500 µg |
|
3209 |
ICC ⋅ N ⋅ WB |
G665 |
100 µg ⋅ 25 µg ⋅ 500 µg |
|
ICC ⋅ N ⋅ WB |
I-141 |
100 µg ⋅ 25 µg |
||
N ⋅ WB |
I-851 |