Anti-Human HLA-DQ – Purified In vivo GOLD™ Functional Grade

Pricing & Details

  
Clone
1a3
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
HLA-DQ Monomorphic
Isotype
Mouse
IgG2a
Applications
B
,
FC
,
WB
Prod No.
Size
Price
Avail.
Qty
Add to cart
H262-1.0 mg
1.0 mg
$95.00
In stock
H262-5.0 mg
5.0 mg
$298.00
In stock
H262-25 mg
25 mg
$775.00
In stock
H262-50 mg
50 mg
$1,275.00
In stock
H262-100 mg
100 mg
$1,998.00
In stock
  

Antibody Details

Reactivity Species
Human
Host Species
Mouse
Immunogen
Unknown
Product Concentration
≥ 2.0 mg/ml
1.0 mg/ml
Endotoxin Level
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Formulation
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium, calcium or preservatives added.
Product Preparation
Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Storage and Handling
Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
RRID
AB_LEINCO
Specificity
Anti-HLA-DQ (clone 1a3) recognizes a monomorphic epitope present on HLA-DQ molecules of the human class II major histocompatibility complex (MHC). Anti-HLA-DQ does not react with HLA-DR or HLA-DP molecules.
Antigen Distribution
The HLA-DQ antigen is present on approximately 10% of peripheral blood lymphocytes. This antibody reacts with virtually all B-cell lines and some tissue macrophages and dendritic cells.

Antigen Details

Protein
HLA-DQ
Ligand/Receptor
CD3/TCR, CD4

References & Citations

1. Bellone, CJ. et al. (1996) J Clin Invest. 97(10):2324-31. PubMed
2. Ikeda Y. et al. (2003) Blood.101(2):621-3. Article Link
3. Wright, TM et al. (2000) J Immunol.164(12):6138-46.PubMed
4. Wright, TM et al. (2001) Arthritis Rheum. 44(7):1654-9. PubMed
5. Nishikawa, Takeji et al. (2000) Journal of Investigative Dermatology 114(1): 88-94. PubMed
6. Shookster et al. (1987) Human Immunol. 20:59
Flow Cytometry
General Western Blot Protocol
  

Formats Available

Products are for research use only. Not for use in diagnostic or therapeutic procedures.